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See full list on redmag ir medilib ir uptodate show 8465medilib ir uptodate show 10088Antidepressants are also a reasonable option for women who responded well to medications for past episodes of depression and for women with a history of severe depression For pregnant women with severe depression, experts suggest selective serotonin reuptake inhibitors (SSRIs) as initial treatment, rather than other antidepressants Dec 4, 2023 · A study of an administrative claims database found that among patients (n >130,000) who started antidepressant monotherapy for a new episode of depression, switching occurred in 9 percent [1] This topic discusses switching from one antidepressant drug to another Fluoxetine is approved for the treatment of unipolar major depressive disorder If treatment for major depressive disorder is initiated for the first time in patients planning to become pregnant, agents other than fluoxetine are preferred (use of fluoxetine is not preferred for use during pregnancy) (Larsen 2015) Fluoxetine is approved for use in children with MDD (aged 8 years and older) and obsessive-compulsive disorder (OCD; aged 7 years and older) Sarafem is not approved for use in children DRUGS USED IN DEPRESSION Selective Serotonin Reuptake Inhibitors (SSRls) Drugs : fluoxetine , paroxetine, sertraline, citalopram, fluvoxamine Mechanism: selective blockade of 5HT reuptake Uses: Major depression OCD Bulimia Anxiety disorders (chronic treatment acute, benzodiazepines) Premenstrual dysphoric disorder (PMDD) The pharmacology, administration, and side effects of atypical antidepressants are reviewed here Choosing a regimen for the initial treatment of depression and treatment of resistant depression is discussed separately, as are other antidepressant drug classes: (See "Major depressive disorder in adults: Approach to initial management" )This topic reviews the pharmacology, administration, and side effects of SNRIs Choosing a regimen for the initial treatment of major depression and treatment of resistant depression is discussed separately, as are other antidepressant drug classes: (See "Major depressive disorder in adults: Approach to initial management" )Dec 5, 2023 · Desvenlafaxine , duloxetine, and venlafaxine are more potent inhibitors of serotonin reuptake than norepinephrine reuptake, whereas levomilnacipran and milnacipran preferentially block reuptake of norepinephrine [2,3,8,9] اگر شما همچنین از داروی الانزاپین(Zyprexa) استفاده می‌کنید، راهنمای دارو Zyprexa را بخوانید و تمام هشدارها و دستورالعمل‌های ارائه‌شده به بیمار در مورد این دارو را مطالعه کنید اگر شما همچنین پیموزید یا تیوریدازین را مصرف می‌کنید، یا اگر از فرم تزریقی متیلن بلو استفاده می‌کنید، نباید از این دارو استفاده کنید اگر شما از یکی از مهار کننده های مونوآمی Additional information about each drug and its inhibition of hepatic enzymes can be found in the individual drug information topics (included within UpToDate) in the section on Metabolism Transport Effects Among the many potential drug-drug interactions that may occur with SSRIs is the interaction between fluoxetine or paroxetine and tamoxifen medilib ir uptodate show 14675medilib ir uptodate show 86265Additional information about discontinuing antidepressants is discussed separately (See "Discontinuing antidepressant medications in adults" ) Side effects — Nefazodone can injure the liver; the estimated incidence of hepatotoxicity based upon a national registry in Spain is 29 cases per 100,000 patients per year medilib ir uptodate show 7704Usual dose: Olanzapine 6 to 12 mg fluoxetine 25 to 50 mg Safety of daily doses of olanzapine >18 mg fluoxetine >75 mg have not been evaluated Depression, treatment resistant Depression, treatment resistant: Oral: Initial: Olanzapine 6 mg fluoxetine 25 mg once daily in the evening Adjust dose based on response and tolerability We generally wait a few days (eg, two to three) before starting the new antidepressant When switching antidepressants, discontinuation symptoms that occur as a result of stopping the current drug may be mistaken as adverse side effects of the new drug that is started Discontinuation symptoms are discussed separately medilib ir uptodate show 4866Mar 7, 2010 · Materials and Methods: In a prospective clinical trial, we used citalopram hydrobromide as a salvage agent in 16 newly married men with premature ejaculation who experienced a history of unsuccessful treatment with fluoxetine hydrochloride Specific drugs and indications – The selective serotonin reuptake inhibitors (SSRIs) include citalopram, escitalopram, fluoxetine , fluvoxamine, paroxetine, and sertraline SSRIs are frequently first-line agents for depressive disorders because of their efficacy, tolerability, and general safety in overdose medilib ir uptodate show 85816medilib ir uptodate show 1716Central nervous system stimulants— Medications that stimulate the nervous system (eg, amphetamine, dextroamphetamine, methylphenidate, modafinil) have profound effects on both the quality and architecture of sleep [23,24] Sleep quality – CNS stimulants increase the latency to sleep onset and increase wakefulness during the sleep period medilib ir uptodate show 1713Switching antidepressants: Evidence for ideal antidepressant switching strategies in pediatric patients is sparse; strategies described in pediatric guidelines include a conservative approach (tapering and discontinuing the antidepressant before adding the second) and cross-titration (gradually discontinuing the first antidepressant while at medilib ir uptodate show 8605
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