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    Prednisolone belongs to the corticosteroid class, and several generic versions exist under names like Prednisol, Prelone, or Omnipred. These are chemically identical to brand-name Prednisolone but typically more affordable. For those seeking alternatives within the same drug class, options like methylprednisolone (Medrol) or dexamethasone (Decadron) may be prescribed, though they differ in potency and duration.

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    True over-the-counter (OTC) corticosteroids like hydrocortisone creams exist for topical use, but oral Prednisolone requires a prescription. Some countries permit low-dose corticosteroid formulations without a prescription, but these are not universally available. For systemic inflammation, alternatives such as ibuprofen or naproxen (NSAIDs) might be considered, though they lack the immunosuppressive properties of Prednisolone.

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