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do not substitute on a mg to mg basis; retitrate if switching between products severe intractable cancer pain, adjunct tx [individualize dose epidurally] Start: 0 5 mcg kg h epidurally; Info: taper dose over 2-4 days to D C ADHD [extended-release form, 6-17 yo]Clonidine is a sympatholytic agent with multiple therapeutic indications, used mainly as an antihypertensive agent It can be useful also in the context of the broad spectrum of dysautonomia (PoTS or autonomic failure) with cardiovascular manifestations such as supine hypertension or orthostatic hypotension due to its multiple effects on central and peripheral pre- and post-synaptic alpha Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors 2 This activity is useful for the treatment of hypertension, severe pain, and ADHD 8,9,10,11 Clonidine was granted FDA approval on 3 September 1974 8go drugbank com drugs DB00575 nausea or vomiting Rare blurred vision decreased interest in sexual intercourse hair loss or thinning of the hair inability to have or keep an erection leg cramps loss in sexual ability, desire, drive, or performance muscle or joint pain Find patient medical information for clonidine HCl oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings Clonidine functions through agonism of alpha-2 adrenoceptors which have effects such as lowering blood pressure, sedation, and hyperpolarization of nerves 2 It has a long duration of action as it is given twice daily and the therapeutic window is between 0 1mg and 2 4mg daily 8,9,10,11 Mechanism of actionCertified & Verified Doctors Will Answer All Your Medical Questions Get Accurate Answers To Your Medical Questions By Verified Doctors --- drugs com clonidine htmlgo drugbank com salts DBSALT000538Clonidine Tablets help to relax blood vessels in the heart and other parts of the body such as the brain or skin As a result, it helps treat menopausal hot flushes or sweats Menopause occurs anywhere around the age of 40-58, and it refers to a phase in a women’s life when she no longer has her period Clonidine Tablets may take 2 to 4 weeks Common clonidine side effects may include: drowsiness, dizziness; feeling tired or irritable; dry mouth; constipation, loss of appetite; or sleep problems (insomnia), nightmares This is not a complete list of side effects and others may occur Call your doctor for medical advice about side effects --- drugs com tips clonidine-patient-tipsStopping clonidine too suddenly can lead to side effects, such as high blood pressure, nervousness, agitation, headache, and tremor Sometimes these symptoms can be life-threatening Your risk is higher if you're taking a higher dose of clonidine or if you're also taking beta-blockers, such as carvedilol (Coreg) Some experts state usual dosage is 0 1–0 3 mg (conventional tablets) every 6–8 hours, with dosage guided by withdrawal symptoms and adverse effects Other experts recommend initial 0 1-mg test dose (conventional tablets); consider 0 2 mg in patients with severe withdrawal or in those weighing >200 pounds (91 kg) May 31, 2024 · Common clonidine side effects may include: drowsiness, dizziness; feeling tired or irritable; 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